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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4b0eaa4249043251fceb455ae28d58e7d6386c0dac031a17f9b3d64c45321a' 
  AND token = 'oeGmKx3Suel356relf11WK8LArKzENyOPnqms7NC/ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}