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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3f0cc673a8061be8cce978c0ef2d9e6830cb725913aaecb94fa95717276083' 
  AND token = 'RIa68Q7Famb+kMmE5L+dJud4HKmZjfMU9twS1QiIBIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}