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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb0c3fc2c53a5b487ed46e226e11329e6b63a5a8124df1c6ab77daacd3711188' 
  AND token = 'zRWK2NWnHFxd6zqHPjOO9jII5QMPyXb8/0PhQXHfC5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}