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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08981650531e06441d873e853e40c03c063b6551eb1acdca3a6a279d2b9faaf8' 
  AND token = 'N/1dZUqaR9tnr9OdAFcKY6SS8nwG3ehIf/on22yC2dU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}