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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d01b2bac839f51145621c2121fa9b8f779806ae45bce768512d4bdc2583295' 
  AND token = '8U/rEqr22Xqx6YP1c2uFK/2oQqXZgZU97Lgkx1JKgjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}