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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6583aea52b22168db94a9c9faf9456221d6d9de860606d1d8748b0cd4acf0980' 
  AND token = 'pYMus9F66xbTdVk/fmmwT9XrGSmTMnzyemXLy12XoF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}