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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a44997b294c7f0e190dafcf4e14735c77eb639edc7dea28ede1f609af29c6017' 
  AND token = '5MifDwzAQSJnKbxka5hUDuzer1q8CwOOTKJRCp04Kk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}