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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e412cb03298cc0ba2495aac22a8629160b0f36e7d1c68d5ef9996495e977cff1' 
  AND token = 'rzHThowkDd0byPNxhA3PYDmB89jjCs9Xx8+TVGjj1SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}