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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af394aa024350b51edaa9b20e51cc7ebf0a7a0885bb0ff4d97dbeba2b8850b41' 
  AND token = 'xdRd7llMlqQtEc5E4oXJxtImN1p8R5Jo3N1jJHXjy/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}