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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85b299d9c372f6c67e34b5d4b5fecdd4959d257bb03aaa08d4eed53c06755f3a' 
  AND token = 'LdeunEyanS3SS1zf6nXxehzxvSn4N/9ZwUlbw+bTsfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}