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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef04fb523c72363931e0e529d4bd96f92f44b13106a5d53221426055bb60386' 
  AND token = '59YdRRnoIOURzDHTh7VqCvXjihTV5no4rr4AKheEN0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}