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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c9f1eca9763661961f4b6e9a9c2fd37b7c8cb30336a96de9b135d15a8681bb' 
  AND token = 'S6Nl1049NVo9a5OtwRzpohz5QxA6XLhPgByq/uCHN/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}