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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2325db93efccf120d4c2a272eb1ba8c90a558c64e200109d4c9143e9c187cf2e' 
  AND token = 'PnGhyYtHtk9JhECYjBcBo1UEkWKi0dLh0PufF7OYIsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}