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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ddab80590e6212de1d1a461fc0cd5b9f0d856b21dd280f796487db25e6bc849' 
  AND token = '6rd5RiX4hgxd2xfNF7MySP+4RPNOoXRfkOe3mO4Iz/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}