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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c684ab78c4c8410bcbe3b6ef62e1b00abe033b883a0ea01360c6c414ef8a6c50' 
  AND token = 'kQQmyRjkARb+x1I/AIWyQf9knUsTAQmAVRxrSktSfwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}