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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09a7818953804013035ce722b297fe39aa6e2abb1cb6073fbdeeea7418735324' 
  AND token = 'vO3BncCKSIrDH2K4vk1MVo7ikHhgvjyBos6Ye9oJ7so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}