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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f085eae94c3ce75992efb243bf2d5cc0d289f7e2c61a366a693556d7a7095af5' 
  AND token = 'a0cT+oFBlsmOGWRdt2v51Xtd2xVUWLsPw7OKT11S+kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}