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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53db6a8eac1f63d8e11c5c1c112b4643c9b0154fb9a792237cb67332a9ac1fac' 
  AND token = 'm9GdvWBwpU1oqbMZEfqDhg3WhZSiaJaoxhKH13EH+No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}