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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f6b27ec06f705974f1de5c7cf353e6d4570e7713df043d1a7eafad3820b81fb' 
  AND token = 'joR3vzlr98vTLbhNBUtoDVAlWE4ZTG9Wa8+yU2F7bPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}