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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91282b15d80165be6b3045ebaaf1f7b8330c34d8a83ea39ced1a7f8c471695f0' 
  AND token = 'fRjPhy4vOwjQ3LLmda2cygyKjJXvs7tnSwxxSlQ3zOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}