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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c8ce949a88f0da317f6070f2ab35e80f65460e5728b541cfb77fef30529c47c' 
  AND token = 'moLyHf+464vigXfUnAkRjCC//Nv+pmIj3X/9O19POKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}