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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7590a71d29fb9df75501485e47165a9d5faa6595df3772333bd36c6a3d588707' 
  AND token = '7BDdiw2ivhcwxN5CEadbiCi19PMIaaDNUslYt5aLdks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}