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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80437501fb76750bd10c5f8759257b7361fe3ddc62dc58a0e95742b1fec76142' 
  AND token = 'tCEgYZOx4YKK3feGEHMwObFhGTAIfETHGgiZ3xgzMIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}