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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2288060d87863d9da831e659555e75e87456da8349bdb7896d1d7055885ed1b3' 
  AND token = 'wA6xGVVkuUxrh3cvXk2hSIvTGSWOWmN3DW/nWYkge+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}