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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42bf6d9cad9a4c6190f6427fcf8e7788831a76f0bba622f2f0ecd5df9d9f01da' 
  AND token = 'pWjO7tl7UpBU0Gh7kicm2fpqRlT5w2XzuZxfRDD7a14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}