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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6cae8acb5d2a52fe9a9f512d689e5bc8bfafd645afd0848405b55c72b1ad88a' 
  AND token = 'vdCW2MU/MLe//fTI1Sg9aaXCFmk4IT1Lz67xCMLZS3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}