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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2ff4b1b8817542d1151382ed1142846ad7247cb07f2ab69c6f5a0a696cf18d0' 
  AND token = 'lO5r67WJz7pxovWUbSSBMp7jj/aBeUUeJopNj25o808=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}