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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d414eeae56f849abf4de4855cd070677734dd1fb87b3f731fb092b95e4ed307' 
  AND token = '3VeMB6V1hDhLOw3J2lOPhAA4R96XfQJRj7fYQ+SzQvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}