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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '158ea284002b7f709b5771d9f17008ece584a27d66297e52ef438c4868677294' 
  AND token = 'RDEDgzcY/vHlzMziQ4j2f7LBgVlFkRLXJtEHsmLILTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}