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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c3d1aeb4ef5a040cf559dddefb15572603d97c42da24b75660b47c14f541e73' 
  AND token = 'nijdiq2qzrcEEIjwVgSNW6zbBoo+LheXyzTMnYpRGsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}