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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21fa35598770d7f80c6aac7896bf3f52de6e1b785b9673bda4413b1b466b09c3' 
  AND token = 'PuCjSsfDCbt9SYYTyQM9e4u36RS5RMCKqBobMgUbjhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}