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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a706e0f10035aa5f77faf155a4105491e54cf6d884f6a1548b10e90b6a016be' 
  AND token = 'F4JK5raLhoxKRmZErwx3XdaeAw2OrNDi5TBQ59gjV9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}