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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25483ccf1ae842efba4928e772e6dea21a783b5878b09a37f19095df329ac603' 
  AND token = 'fppCp7Zeyta/DTxIlRvaZ+We3NM/RnY7+N2kOtznX70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}