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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaf456a3b14c8d18d636978731cccbc9a58eed3e3a9e4b7ec98a0d040da6382f' 
  AND token = 'fgA8zHc9w1JXMn2aF5zhPF914Sf5UHCoeI87+Qw6X6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}