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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a37053dee0b9e6cbf726bc6c895da90dd0f9453315e6e4e585afb4bf53b9f5' 
  AND token = 'x9FVMFEFndbD6nh21Et2JDCzSwhjO9GoNdQoex9di7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}