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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40ac0c192fe34bfc985bb1b80ab0c6dc55744339cc90e9f136ddf66ab38ec291' 
  AND token = 'etOtXNeI0G27mS98DWnGFZhKlsl34Poq6AVx8yWs45g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}