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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a973be7303d28da7cdd8d20abbd30de423d744644fb08d162e54b3e2e924630' 
  AND token = 's2dtkvMs7R6bJEtQ/BYvkrNchIAgXNZtksPWQdbOR7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}