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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65176d48bb1f4593b87aab4957e92281eb2b087c0e37b186570c87d2403de7a2' 
  AND token = 'RsFzXHo5S/WnvUjHgm870ch2P9jr66tXWwF+Mv5zfAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}