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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c3c85d3b7faefd6dc30ba4d9ff82b5dae27bf1ee4cbd9d7893f46338f153f8' 
  AND token = 'woM1Y73OaEjTwGJn2W2tNcUcnPZRQuOANSdEnVDyhqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}