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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b09a808e00cdcac784d4ada8ddd4485a4d76d732225d7519be62782d89c1a37' 
  AND token = 'N3JME8wKN75cZo4qvYTX7OSaGFuLqpDva814JMLWHZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}