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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54314bfbc7bc116e02d0ce122f637cfe77567fb3cec5422df9c6711bb03ca3a0' 
  AND token = 'Hb3S/DojqmW72hgC6vMJuqLs+Kj9KJr2O6fJ7cG2bx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}