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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d111d61d73756d7e47f95493a1d1ac9f834eeac460af5f857af181c8e4eff36' 
  AND token = 'wtU2gJ+DPq6qtAXHw3KkfIqtkTc6ZMoxXz3vFYE2QYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}