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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd81f55147f1b8ed50fcdf2563378e0a8e327209ce9f933d7cada8aa59662ab4' 
  AND token = '6h5Rag3wda0rpblhR8fcvR9AnXFn3Zr9ToEgIX4cbcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}