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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749bd49b77a8afc70f72ca0c6da5b26cb40f7f90d7e6d05a68c902bea469b1d3' 
  AND token = 'DLEec06uThNOV2kUzux2CoX0rEVgq3gm/1eAUEvEbW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}