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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52aed5f53e5df22ccaae6a83ec82d4b4bd1ebe1f455d109c752606fa4065ca5a' 
  AND token = 'i12cC8W+ddgsrVBpz3Kf5PWaYEYW+paqMrRdGTJ81Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}