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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8889cff46dd94d255562dff1e947d6f2ba5c308acc66d75c0af737b4e1fa1bd3' 
  AND token = 'me7bFOcVnu0jPquzNC2dqxvYIG8NKCxiDAfn7XrQUuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}