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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e36f628bf0fa2a43e2ddbaaa88beb4946adaebddee9ef2527c0d0c3ae1bbc1' 
  AND token = '6NX8Tsrf1dlUT9PbSj+sE+Kr+Epty7RTcLt/f12o348=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}