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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53251d0ad90806db5a776ab5f5301445d93a2f0e2289d40639aecf0a89a41a0c' 
  AND token = 'wPfQnNSFEkvwLst1kF/eCL6FNwfKVZtizghc3R3gA1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}