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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9ed2a092bf595dde1527f62795b8c9307cf64323d3f90eef62d554431ceb90' 
  AND token = 'Mzz8QBF1It+xbZ+PkTqL5GUTZGl83bOftrX+VRVp1s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}