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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed05ebe419642c13e00587d490891a243ba4269ca5e36fad1aef6d49578152d4' 
  AND token = 'aC2R9fPN/ltRTEz3Sc4LOuhB58vWM5XTWXrINoaHVrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}